

Maybe in the wake of their surrender and Odo rejoining them the Founders step back or even go into isolation entirely. The Dominion collapses and there is widespread fighting in the gamma quadrant as different factions seek to take the Founders place. The new series could primarily be set in that quadrant. Maybe the Federation established a foothold in the gamma quadrant so that they controlled both sides of the wormhole and the Enterprise is there to expand the Federation’s influence. That would give the writers freedom to introduce new antagonists because DS9 did very little actual exploration of the gamma quadrant.
Edit: gamma not delta
Al Bundy peaked in highschool, never went to college, was a shoe salesman at the mall. Al Bundy had an, at least, three bedroom single family home in a nice neighborhood, supported a family of four plus a dog on his single income, had ample free time to spend with family and friends and to spend on hobbies.
Al Bundy: Failure and constant butt of jokes in the 1980s, unobtainable vision of success in the 2020s